Screening and characterization of inhibitory vNAR targeting nanodisc-assembled influenza M2 proteins

Influenza A virus poses a constant challenge to human health. The highly conserved influenza matrix-2 (M2) protein is an attractive target for the development of a universal antibody-based drug. However, screening using antigens with subphysiological conformation in a nonmembrane environment signifi...

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Detalles Bibliográficos
Autores principales: Yu, Chuandi, Ding, Wen, Zhu, Lei, Zhou, Yuhang, Dong, Yingkui, Li, Ling, Liu, Juanjuan, Wang, Yizhuo, Li, Zehua, Zhu, Lina, Chen, FaJun, Ruan, Maosen, Qian, Dongming, Wang, Yujuan, Wu, Bo, Xu, Huangtao, Li, Ming, Bi, Yunchen, Wang, Hao, Wang, Weiqian, Chao, Peng, Xing, Lei, Shen, Bing, Dai, Han, Zha, Lisha, Zhao, Hongxin, Wang, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771723/
https://www.ncbi.nlm.nih.gov/pubmed/36570769
http://dx.doi.org/10.1016/j.isci.2022.105736

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