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SOX9 and TCF transcription factors associate to mediate Wnt/β-catenin target gene activation in colorectal cancer

Activation of the Wnt/β-catenin pathway regulates gene expression by promoting the formation of a β-catenin–T-cell factor (TCF) complex on target enhancers. In addition to TCFs, other transcription factors interact with the Wnt/β-catenin pathway at different levels to produce tissue-specific pattern...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Aravinda-Bharathi, Burby, Peter E., Adiga, Kavya, Cadigan, Ken M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771724/
https://www.ncbi.nlm.nih.gov/pubmed/36423688
http://dx.doi.org/10.1016/j.jbc.2022.102735