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SOX9 and TCF transcription factors associate to mediate Wnt/β-catenin target gene activation in colorectal cancer
Activation of the Wnt/β-catenin pathway regulates gene expression by promoting the formation of a β-catenin–T-cell factor (TCF) complex on target enhancers. In addition to TCFs, other transcription factors interact with the Wnt/β-catenin pathway at different levels to produce tissue-specific pattern...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771724/ https://www.ncbi.nlm.nih.gov/pubmed/36423688 http://dx.doi.org/10.1016/j.jbc.2022.102735 |