Cargando…

SOX9 and TCF transcription factors associate to mediate Wnt/β-catenin target gene activation in colorectal cancer

Activation of the Wnt/β-catenin pathway regulates gene expression by promoting the formation of a β-catenin–T-cell factor (TCF) complex on target enhancers. In addition to TCFs, other transcription factors interact with the Wnt/β-catenin pathway at different levels to produce tissue-specific pattern...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ramakrishnan, Aravinda-Bharathi, Burby, Peter E., Adiga, Kavya, Cadigan, Ken M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771724/ https://www.ncbi.nlm.nih.gov/pubmed/36423688 http://dx.doi.org/10.1016/j.jbc.2022.102735

Ejemplares similares

Wnt target enhancer regulation by a CDX/TCF transcription factor collective and a novel DNA motif
por: Ramakrishnan, Aravinda-Bharathi, et al.
Publicado: (2021)

Repression of Wnt/β-catenin signaling by SOX9 and Mastermind-like transcriptional coactivator 2
por: Sinha, Abhishek, et al.
Publicado: (2021)

Wnt-Mediated Repression via Bipartite DNA Recognition by TCF in the Drosophila Hematopoietic System
por: Zhang, Chen U., et al.
Publicado: (2014)

Wnt target genes and where to find them
por: Ramakrishnan, Aravinda-Bharathi, et al.
Publicado: (2017)

Diffusion and function of Wnt ligands
por: Stewart, Richard A., et al.
Publicado: (2019)

Structure-Function Analysis of the C-clamp of TCF/Pangolin in Wnt/ß-catenin Signaling
por: Ravindranath, Aditi, et al.
Publicado: (2014)

SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells
por: Mukherjee, Shreyasi, et al.
Publicado: (2022)

VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs
por: Zhang, Haifeng, et al.
Publicado: (2021)

Claudin-7 deficiency promotes stemness properties in colorectal cancer through Sox9-mediated Wnt/β-catenin signalling
por: Xu, Chang, et al.
Publicado: (2021)

The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β-Catenin/TCF Regulated Transcription
por: Abdel-Rahman, Wael M., et al.
Publicado: (2016)

Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer
por: Bian, Jia, et al.
Publicado: (2020)

Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/β-catenin signaling
por: Leung, Carmen Oi-Ning, et al.
Publicado: (2016)

KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer
por: Yao, Hanhui, et al.
Publicado: (2022)

Pja2 Inhibits Wnt/β-catenin Signaling by Reducing the Level of TCF/LEF1
por: Song, Yonghee, et al.
Publicado: (2018)

Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/β-catenin transcriptional activity
por: He, Xiaoli, et al.
Publicado: (2017)

Interplay Between SOX9, Wnt/β-Catenin and Androgen Receptor Signaling in Castration-Resistant Prostate Cancer
por: Khurana, Namrata, et al.
Publicado: (2019)

FGF9 Promotes Expression of HAS2 in Palatal Elevation via the Wnt/β-Catenin/TCF7L2 Pathway
por: Sun, Yidan, et al.
Publicado: (2022)

Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression
por: Wallmen, Britta, et al.
Publicado: (2012)

Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with β-Catenin/TCF4 Interaction in Colorectal Cancer Cells
por: Li, Xingyao, et al.
Publicado: (2013)

Long non-coding RNA lncTCF7 activates the Wnt/β-catenin pathway to promote metastasis and invasion in colorectal cancer
por: Li, Tengyu, et al.
Publicado: (2017)

The function of BCL9 in Wnt/β-catenin signaling and colorectal cancer cells
por: de la Roche, Marc, et al.
Publicado: (2008)

Tcf-3 expression and β -catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour)
por: Tejpar, S, et al.
Publicado: (2001)

The Role of the C-Clamp in Wnt-Related Colorectal Cancers
por: Ravindranath, Aditi J., et al.
Publicado: (2016)

Wnt–β-catenin–Tcf-4 signalling-modulated invasiveness is dependent on osteopontin expression in breast cancer
por: Ravindranath, A, et al.
Publicado: (2011)

Nuclear Dvl, c-Jun, β-catenin, and TCF form a complex leading to stabiLization of β-catenin–TCF interaction
por: Gan, Xiao-qing, et al.
Publicado: (2008)

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/β-catenin targets
por: Weise, Andreas, et al.
Publicado: (2010)

SOX9 is an atypical intestinal tumor suppressor controlling the oncogenic Wnt/ß-catenin signaling
por: Prévostel, Corinne, et al.
Publicado: (2016)

SOX9 drives the epithelial–mesenchymal transition in non-small-cell lung cancer through the Wnt/β-catenin pathway
por: Huang, Jing-Qiang, et al.
Publicado: (2019)

SOX8 promotes tumor growth and metastasis through FZD6-dependent Wnt/β-catenin signaling in colorectal carcinoma
por: Li, Chen, et al.
Publicado: (2023)

Purified Wnt5a Protein Activates or Inhibits β-Catenin–TCF Signaling Depending on Receptor Context
por: Mikels, Amanda J, et al.
Publicado: (2006)

Wnt/β‐catenin signaling in brain development and mental disorders: keeping TCF7L2 in mind
por: Bem, Joanna, et al.
Publicado: (2019)

Bipartite Recognition of DNA by TCF/Pangolin Is Remarkably Flexible and Contributes to Transcriptional Responsiveness and Tissue Specificity of Wingless Signaling
por: Archbold, Hilary C., et al.
Publicado: (2014)

Wnt2 complements Wnt/β-catenin signaling in colorectal cancer
por: Jung, Youn-Sang, et al.
Publicado: (2015)

Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network
por: Mukherjee, Shreyasi, et al.
Publicado: (2020)

Securin (hPTTG1) expression is regulated by β-catenin/TCF in human colorectal carcinoma
por: Hlubek, F, et al.
Publicado: (2006)

S100A4/TCF Complex Transcription Regulation Drives Epithelial-Mesenchymal Transition in Chronic Sinusitis Through Wnt/GSK-3β/β-Catenin Signaling
por: Gong, Ningyue, et al.
Publicado: (2022)

TM4SF1 promotes EMT and cancer stemness via the Wnt/β-catenin/SOX2 pathway in colorectal cancer
por: Tang, Qiang, et al.
Publicado: (2020)

Endosomal Adaptor Proteins APPL1 and APPL2 Are Novel Activators of β-Catenin/TCF-mediated Transcription
por: Rashid, Sajid, et al.
Publicado: (2009)

Tcf3 Represses Wnt–β-Catenin Signaling and Maintains Neural Stem Cell Population during Neocortical Development
por: Kuwahara, Atsushi, et al.
Publicado: (2014)

SOX30 Inhibits Tumor Metastasis through Attenuating Wnt-Signaling via Transcriptional and Posttranslational Regulation of β-Catenin in Lung Cancer
por: Han, Fei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_15k0p50l8r57ih4dik0gn6grsn