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Loss of HER2 in breast cancer: biological mechanisms and technical pitfalls

Loss of HER2 in previously HER2-positive breast tumors is not rare, occurring in up to 50% of breast cancers; however, clinical research and practice underestimate this issue. Many studies have reported the loss of HER2 after neoadjuvant therapy and at metastatic relapse and identified clinicopathol...

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Detalles Bibliográficos
Autores principales: Morganti, Stefania, Ivanova, Mariia, Ferraro, Emanuela, Ascione, Liliana, Vivanet, Grazia, Bonizzi, Giuseppina, Curigliano, Giuseppe, Fusco, Nicola, Criscitiello, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771738/
https://www.ncbi.nlm.nih.gov/pubmed/36627895
http://dx.doi.org/10.20517/cdr.2022.55