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Mechanisms of neratinib resistance in HER2-mutant metastatic breast cancer

Human epidermal growth factor receptor 2 (HER2) is a major drug target and clinical biomarker in breast cancer treatment. Targeting HER2 gene amplification is one of the greatest successes in oncology, resulting in the use of a wide array of HER2-directed agents in the clinic. The discovery of HER2-...

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Detalles Bibliográficos
Autores principales: Eli, Lisa D., Kavuri, Shyam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771739/
https://www.ncbi.nlm.nih.gov/pubmed/36627899
http://dx.doi.org/10.20517/cdr.2022.48