Caffeine treatment started before injury reduces hypoxic–ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization

BACKGROUND: Reducing neuroinflammatory damage is an effective strategy for treating white-matter damage (WMD) in premature infants. Caffeine can ameliorate hypoxia–ischemia-induced brain WMD; however, its neuroprotective effect and mechanism against hypoxic–ischemic WMD remain unclear. METHODS: We u...

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Detalles Bibliográficos
Autores principales: Yang, Liu, Yu, Xuefei, Zhang, Yajun, Liu, Na, Xue, Xindong, Fu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Basic Science Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771815/
https://www.ncbi.nlm.nih.gov/pubmed/35220399
http://dx.doi.org/10.1038/s41390-021-01924-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771815/
https://www.ncbi.nlm.nih.gov/pubmed/35220399
http://dx.doi.org/10.1038/s41390-021-01924-6

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