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Benzimidazoles cause lethality by inhibiting the function of Caenorhabditis elegans neuronal beta-tubulin

Parasitic nematode infections cause an enormous global burden to both humans and livestock. Resistance to the limited arsenal of anthelmintic drugs used to combat these infections is widespread, including benzimidazole (BZ) compounds. Previous studies using the free-living nematode Caenorhabditis el...

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Detalles Bibliográficos
Autores principales: Gibson, Sophia B., Ness-Cohn, Elan, Andersen, Erik C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771835/
https://www.ncbi.nlm.nih.gov/pubmed/36332489
http://dx.doi.org/10.1016/j.ijpddr.2022.10.004