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Current and emerging target identification methods for novel antimalarials

New antimalarial compounds with novel mechanisms of action are urgently needed to combat the recent rise in antimalarial drug resistance. Phenotypic high-throughput screens have proven to be a successful method for identifying new compounds, however, do not provide mechanistic information about the...

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Detalles Bibliográficos
Autores principales: Challis, Matthew P., Devine, Shane M., Creek, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771836/
https://www.ncbi.nlm.nih.gov/pubmed/36410177
http://dx.doi.org/10.1016/j.ijpddr.2022.11.001