ATP-citrate lyase inhibitor improves ectopic lipid accumulation in the kidney in a db/db mouse model

AIM: We evaluated a novel treatment for obesity-related renal, an ATP-citrate lyase (ACL) inhibitor, to attenuate ectopic lipid accumulation (ELA) in the kidney and the ensuing inflammation. MATERIALS AND METHODS: An ACL inhibitor was administered intragastrically to 12-week-old db/db mice for 30 da...

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Detalles Bibliográficos
Autores principales: Zhan, Zishun, Li, Aimei, Zhang, Wei, Wu, Xueqin, He, Jinrong, Li, Zhi, Li, Yanchun, Sun, Jian, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771989/
https://www.ncbi.nlm.nih.gov/pubmed/36568100
http://dx.doi.org/10.3389/fendo.2022.914865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771989/
https://www.ncbi.nlm.nih.gov/pubmed/36568100
http://dx.doi.org/10.3389/fendo.2022.914865

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