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Mathematical modeling and simulation of thyroid homeostasis: Implications for the Allan-Herndon-Dudley syndrome

INTRODUCTION: A mathematical model of the pituitary-thyroid feedback loop is extended to deepen the understanding of the Allan-Herndon-Dudley syndrome (AHDS). The AHDS is characterized by unusual thyroid hormone concentrations and a mutation in the SLC16A2 gene encoding for the monocarboxylate trans...

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Detalles Bibliográficos
Autores principales: Wolff, Tobias M., Veil, Carina, Dietrich, Johannes W., Müller, Matthias A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772020/
https://www.ncbi.nlm.nih.gov/pubmed/36568087
http://dx.doi.org/10.3389/fendo.2022.882788