Aberrant glial activation and synaptic defects in CaMKIIα-iCre and nestin-Cre transgenic mouse models

Current scientific research is driven by the ability to manipulate gene expression by utilizing the Cre/loxP system in transgenic mouse models. However, artifacts in Cre-driver mouse lines that introduce undesired effects and confound results are increasingly being reported. Here, we show aberrant n...

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Detalles Bibliográficos
Autores principales: Alia, Alia O., Jeon, Sohee, Popovic, Jelena, Salvo, Miranda A., Sadleir, Katherine R., Vassar, Robert, Cuddy, Leah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772212/
https://www.ncbi.nlm.nih.gov/pubmed/36543864
http://dx.doi.org/10.1038/s41598-022-26671-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772212/
https://www.ncbi.nlm.nih.gov/pubmed/36543864
http://dx.doi.org/10.1038/s41598-022-26671-4

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