Cargando…
Aberrant glial activation and synaptic defects in CaMKIIα-iCre and nestin-Cre transgenic mouse models
Current scientific research is driven by the ability to manipulate gene expression by utilizing the Cre/loxP system in transgenic mouse models. However, artifacts in Cre-driver mouse lines that introduce undesired effects and confound results are increasingly being reported. Here, we show aberrant n...
Autores principales: | Alia, Alia O., Jeon, Sohee, Popovic, Jelena, Salvo, Miranda A., Sadleir, Katherine R., Vassar, Robert, Cuddy, Leah K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772212/ https://www.ncbi.nlm.nih.gov/pubmed/36543864 http://dx.doi.org/10.1038/s41598-022-26671-4 |
Ejemplares similares
-
hCD2-iCre and Vav-iCre Mediated Gene Recombination Patterns in Murine Hematopoietic Cells
por: Siegemund, Sabine, et al.
Publicado: (2015) -
Optimising the zebrafish Cre/Lox toolbox. Codon improved iCre, new gateway tools, Cre protein and guidelines
por: Tromp, Alisha, et al.
Publicado: (2023) -
Germ-Line Recombination Activity of the Widely Used hGFAP-Cre and Nestin-Cre Transgenes
por: Zhang, Jiong, et al.
Publicado: (2013) -
Synaptic memory and CaMKII
por: Nicoll, Roger A., et al.
Publicado: (2023) -
Synaptic memory requires CaMKII
por: Tao, Wucheng, et al.
Publicado: (2021)