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FANCD2 promotes mitotic rescue from transcription-mediated replication stress in SETX-deficient cancer cells
Replication stress (RS) is a leading cause of genome instability and cancer development. A substantial source of endogenous RS originates from the encounter between the transcription and replication machineries operating on the same DNA template. This occurs predominantly under specific contexts, su...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772326/ https://www.ncbi.nlm.nih.gov/pubmed/36543851 http://dx.doi.org/10.1038/s42003-022-04360-2 |