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FANCD2 promotes mitotic rescue from transcription-mediated replication stress in SETX-deficient cancer cells

Replication stress (RS) is a leading cause of genome instability and cancer development. A substantial source of endogenous RS originates from the encounter between the transcription and replication machineries operating on the same DNA template. This occurs predominantly under specific contexts, su...

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Detalles Bibliográficos
Autores principales: Said, Maha, Barra, Viviana, Balzano, Elisa, Talhaoui, Ibtissam, Pelliccia, Franca, Giunta, Simona, Naim, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772326/
https://www.ncbi.nlm.nih.gov/pubmed/36543851
http://dx.doi.org/10.1038/s42003-022-04360-2