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SIRT3 activation promotes enteric neurons survival and differentiation

Enteric neuron degeneration has been observed during aging, and in individuals with metabolic dysfunction including obesity and diabetes. Honokiol, a naturally occurring compound, is an activator of Sirtuin-3 (SIRT3) that has antioxidant activity. Its role in modulating enteric neuron-specific neuro...

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Detalles Bibliográficos
Autores principales: Balasubramaniam, Arun, Li, Ge, Ramanathan, Anita, Mwangi, Simon Musyoka, Hart, C. Michael, Arbiser, Jack L., Srinivasan, Shanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772335/
https://www.ncbi.nlm.nih.gov/pubmed/36543902
http://dx.doi.org/10.1038/s41598-022-26634-9