Functional investigation of SLC1A2 variants associated with epilepsy

Epilepsy is a common neurological disorder and glutamate excitotoxicity plays a key role in epileptic pathogenesis. Astrocytic glutamate transporter GLT-1 is responsible for preventing excitotoxicity via clearing extracellular accumulated glutamate. Previously, three variants (G82R, L85P, and P289R)...

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Detalles Bibliográficos
Autores principales: Qu, Qi, Zhang, Wenlong, Wang, Ji, Mai, Dongmei, Ren, Siqiang, Qu, Shaogang, Zhang, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772344/
https://www.ncbi.nlm.nih.gov/pubmed/36543780
http://dx.doi.org/10.1038/s41419-022-05457-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772344/
https://www.ncbi.nlm.nih.gov/pubmed/36543780
http://dx.doi.org/10.1038/s41419-022-05457-6

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