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Chickens, more than humans, focus the diversity of their immunoglobulin genes on the complementarity-determining region but utilise amino acids, indicative of a more cross-reactive antibody repertoire

The mechanisms of B-cell diversification differ greatly between aves and mammals, but both produce B cells and antibodies capable of supporting an effective immune response. To see how differences in the generation of diversity might affect overall repertoire diversity, we have compared the diversit...

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Detalles Bibliográficos
Autores principales: Mallaby, Jessica, Ng, Joseph, Stewart, Alex, Sinclair, Emma, Dunn-Walters, Deborah, Hershberg, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772431/
https://www.ncbi.nlm.nih.gov/pubmed/36569888
http://dx.doi.org/10.3389/fimmu.2022.837246