Cargando…

A single administration of hIL-7-hyFc induces long-lasting T-cell expansion with maintained effector functions

Interleukin-7 (IL-7) is an essential cytokine for T-cell homeostatic proliferation and maintenance. Clinical studies have shown the potential benefits of IL-7 therapy in various diseases associated with lymphopenia. However, the kinetics of the T-cell response to a single administration of IL-7 in h...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Sojeong, Lee, Sang Won, Koh, June-Young, Choi, Donghoon, Heo, Minkyu, Chung, Jae-Yong, Lee, Byung Ha, Yang, Se Hwan, Sung, Young Chul, Lee, Howard, Shin, Eui-Cheol, Park, Su-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772483/
https://www.ncbi.nlm.nih.gov/pubmed/36206199
http://dx.doi.org/10.1182/bloodadvances.2021006591