Retinal pigment epithelium extracellular vesicles are potent inducers of age‐related macular degeneration disease phenotype in the outer retina

Age‐related macular degeneration (AMD) is a leading cause of blindness. Vision loss is caused by the retinal pigment epithelium (RPE) and photoreceptors atrophy and/or retinal and choroidal angiogenesis. Here we use AMD patient‐specific RPE cells with the Complement Factor H Y402H high‐risk polymorp...

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Detalles Bibliográficos
Autores principales: Kurzawa‐Akanbi, Marzena, Whitfield, Phillip, Burté, Florence, Bertelli, Pietro Maria, Pathak, Varun, Doherty, Mary, Hilgen, Birthe, Gliaudelytė, Lina, Platt, Mark, Queen, Rachel, Coxhead, Jonathan, Porter, Andrew, Öberg, Maria, Fabrikova, Daniela, Davey, Tracey, Beh, Chia Shyan, Georgiou, Maria, Collin, Joseph, Boczonadi, Veronika, Härtlova, Anetta, Taggart, Michael, Al‐Aama, Jumana, Korolchuk, Viktor I, Morris, Christopher M, Guduric‐Fuchs, Jasenka, Steel, David H, Medina, Reinhold J, Armstrong, Lyle, Lako, Majlinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772497/
https://www.ncbi.nlm.nih.gov/pubmed/36544284
http://dx.doi.org/10.1002/jev2.12295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772497/
https://www.ncbi.nlm.nih.gov/pubmed/36544284
http://dx.doi.org/10.1002/jev2.12295

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