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Skeletal Muscle Nuclei in Mice are not Post-mitotic

The skeletal muscle research field generally accepts that nuclei in skeletal muscle fibers (ie, myonuclei) are post-mitotic and unable to proliferate. Because our deuterium oxide (D(2)O) labeling studies showed DNA synthesis in skeletal muscle tissue, we hypothesized that resident myonuclei can repl...

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Detalles Bibliográficos
Autores principales: Borowik, Agnieszka K, Davidyan, Arik, Peelor, Frederick F, Voloviceva, Evelina, Doidge, Stephen M, Bubak, Matthew P, Mobley, Christopher B, McCarthy, John J, Dupont-Versteegden, Esther E, Miller, Benjamin F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772608/
https://www.ncbi.nlm.nih.gov/pubmed/36569816
http://dx.doi.org/10.1093/function/zqac059