Induction of whole-body gene deletion via R26-regulated tamoxifen-inducible Cre recombinase activity

Germline deletion of certain genes causes embryonic lethality, therefore, understanding the effect of deletion of such genes on mammalian pathophysiology remains challenging. Tamoxifen (TAM)-inducible Cre recombinase is widely used for tissue-specific and temporal induction of gene deletion in mice....

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Detalles Bibliográficos
Autores principales: Kumar, Rahul, Mao, Yun, Patial, Sonika, Saini, Yogesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772612/
https://www.ncbi.nlm.nih.gov/pubmed/36569322
http://dx.doi.org/10.3389/fphar.2022.1018798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772612/
https://www.ncbi.nlm.nih.gov/pubmed/36569322
http://dx.doi.org/10.3389/fphar.2022.1018798

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