Cargando…
Induction of whole-body gene deletion via R26-regulated tamoxifen-inducible Cre recombinase activity
Germline deletion of certain genes causes embryonic lethality, therefore, understanding the effect of deletion of such genes on mammalian pathophysiology remains challenging. Tamoxifen (TAM)-inducible Cre recombinase is widely used for tissue-specific and temporal induction of gene deletion in mice....
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772612/ https://www.ncbi.nlm.nih.gov/pubmed/36569322 http://dx.doi.org/10.3389/fphar.2022.1018798 |