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Cryopreserved platelets compared with liquid-stored platelets for the treatment of surgical bleeding: protocol for two multicentre randomised controlled blinded non-inferiority trials (the CLIP-II and CLIPNZ-II trials)

INTRODUCTION: Cryopreservation at −80°C in dimethylsulphoxide extends platelet shelf-life from 7 days to 2 years. Only limited comparative trial data supports the safety and effectiveness of cryopreserved platelets as a treatment for surgical bleeding. Cryopreserved platelets are not currently regis...

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Detalles Bibliográficos
Autores principales: Reade, Michael C., Marks, Denese C, Howe, Belinda, McGuinness, Shay, Parke, Rachael, Navarra, Leanlove, Charlewood, Richard, Johnson, Lacey, McQuilten, Zoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772641/
https://www.ncbi.nlm.nih.gov/pubmed/36600425
http://dx.doi.org/10.1136/bmjopen-2022-068933