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Tumor-associated neutrophils and macrophages exacerbate antidrug IgG-mediated anaphylactic reaction against an immune checkpoint inhibitor

BACKGROUND: With the increased use of immune checkpoint inhibitors (ICIs), side effects and toxicity are a great concern. Anaphylaxis has been identified as a potential adverse event induced by ICIs. Anaphylaxis is a life-threatening medical emergency. However, the mechanisms and factors that can po...

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Detalles Bibliográficos
Autores principales: Arai, Takahiro, Kokubo, Tomomi, Tang, Ruiheng, Abo, Hirohito, Terui, Ayu, Hirakawa, Jotaro, Akita, Hidetaka, Kawashima, Hiroto, Hisaka, Akihiro, Hatakeyama, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772690/
https://www.ncbi.nlm.nih.gov/pubmed/36543377
http://dx.doi.org/10.1136/jitc-2022-005657