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Upfront BRAF/MEK inhibitors for treatment of high-grade glioma: A case report and review of the literature

BACKGROUND: High-grade gliomas (HGG) with BRAFV600E mutation represent a unique subset of central nervous system tumors. Targeted therapies including BRAF and MEK inhibitors are now being explored as possible new treatment options. METHODS: We report an 18-year-old female with a grade 3 pleomorphic...

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Detalles Bibliográficos
Autores principales: Arbour, Gabrielle, Ellezam, Benjamin, Weil, Alexander G, Cayrol, Romain, Vanan, Magimairajan Issai, Coltin, Hallie, Larouche, Valérie, Erker, Craig, Jabado, Nada, Perreault, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772816/
https://www.ncbi.nlm.nih.gov/pubmed/36567957
http://dx.doi.org/10.1093/noajnl/vdac174