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An isoform-specific function of Cdc42 in regulating mammalian Exo70 during axon formation

The highly conserved GTPase Cdc42 is an essential regulator of cell polarity and promotes exocytosis through the exocyst complex in budding yeast and Drosophila. In mammals, this function is performed by the closely related GTPase TC10, whereas mammalian Cdc42 does not interact with the exocyst. Axo...

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Detalles Bibliográficos
Autores principales: Ravindran, Priyadarshini, Püschel, Andreas W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772827/
https://www.ncbi.nlm.nih.gov/pubmed/36543541
http://dx.doi.org/10.26508/lsa.202201722