Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle

Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). We investigated...

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Detalles Bibliográficos
Autores principales: Masania, Jinit, Wijten, Patrick, Keipert, Susanne, Ost, Mario, Klaus, Susanne, Rabbani, Naila, Thornalley, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772855/
https://www.ncbi.nlm.nih.gov/pubmed/36521306
http://dx.doi.org/10.1016/j.redox.2022.102574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772855/
https://www.ncbi.nlm.nih.gov/pubmed/36521306
http://dx.doi.org/10.1016/j.redox.2022.102574

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