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Neonatal exposures to sevoflurane in rhesus monkeys alter synaptic ultrastructure in later life
Repeated or prolonged early life exposure to anesthesia is neurotoxic in animals and associated with neurocognitive impairment in later life in humans. We used electron microscopy with unbiased stereological sampling to assess synaptic ultrastructure in dorsolateral prefrontal cortex (dlPFC) and hip...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772858/ https://www.ncbi.nlm.nih.gov/pubmed/36567715 http://dx.doi.org/10.1016/j.isci.2022.105685 |