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Neonatal exposures to sevoflurane in rhesus monkeys alter synaptic ultrastructure in later life

Repeated or prolonged early life exposure to anesthesia is neurotoxic in animals and associated with neurocognitive impairment in later life in humans. We used electron microscopy with unbiased stereological sampling to assess synaptic ultrastructure in dorsolateral prefrontal cortex (dlPFC) and hip...

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Detalles Bibliográficos
Autores principales: Fehr, Tristan, Janssen, William G.M., Park, Janis, Baxter, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772858/
https://www.ncbi.nlm.nih.gov/pubmed/36567715
http://dx.doi.org/10.1016/j.isci.2022.105685