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Alzheimer’s disease like neuropathology in Down syndrome cortical organoids
Introduction: Down syndrome (DS) is a genetic disorder with an extra copy of chromosome 21 and DS remains one of the most common causes of intellectual disabilities in humans. All DS patients have Alzheimer’s disease (AD)-like neuropathological changes including accumulation of plaques and tangles b...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773144/ https://www.ncbi.nlm.nih.gov/pubmed/36568886 http://dx.doi.org/10.3389/fncel.2022.1050432 |