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Alzheimer’s disease like neuropathology in Down syndrome cortical organoids

Introduction: Down syndrome (DS) is a genetic disorder with an extra copy of chromosome 21 and DS remains one of the most common causes of intellectual disabilities in humans. All DS patients have Alzheimer’s disease (AD)-like neuropathological changes including accumulation of plaques and tangles b...

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Detalles Bibliográficos
Autores principales: Zhao, Helen H., Haddad, Gabriel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773144/
https://www.ncbi.nlm.nih.gov/pubmed/36568886
http://dx.doi.org/10.3389/fncel.2022.1050432