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Spermidine supplementation influences mitochondrial number and morphology in the heart of aged mice

Aging is associated with cardiac hypertrophy and progressive decline in heart function. One of the hallmarks of cellular aging is the dysfunction of mitochondria. These organelles occupy around 1/4 to 1/3 of the cardiomyocyte volume. During cardiac aging, the removal of defective or dysfunctional mi...

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Detalles Bibliográficos
Autores principales: Messerer, Jil, Wrede, Christoph, Schipke, Julia, Brandenberger, Christina, Abdellatif, Mahmoud, Eisenberg, Tobias, Madeo, Frank, Sedej, Simon, Mühlfeld, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773166/
https://www.ncbi.nlm.nih.gov/pubmed/34958481
http://dx.doi.org/10.1111/joa.13618