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Measuring the Affinities of RNA and DNA Aptamers with DNA Origami-Based Chiral Plasmonic Probes

[Image: see text] Reliable characterization of binding affinities is crucial for selected aptamers. However, the limited repertoire of universal approaches to obtain the dissociation constant (K(D)) values often hinders the further development of aptamer-based applications. Herein, we present a comp...

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Detalles Bibliográficos
Autores principales: Huang, Yike, Ryssy, Joonas, Nguyen, Minh-Kha, Loo, Jacky, Hällsten, Susanna, Kuzyk, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773176/
https://www.ncbi.nlm.nih.gov/pubmed/36480745
http://dx.doi.org/10.1021/acs.analchem.2c04034