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One-Step Sortase-Mediated Chemoenzymatic Semisynthesis of Deubiquitinase-Resistant Ub-Peptide Conjugates

[Image: see text] Post-translational modifications (PTMs) of proteins increase the functional diversity of the proteome and play crucial regulatory roles in cellular processes. Ubiquitination is a highly regulated and reversible PTM accomplished by a complex multistep process with the sequential act...

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Detalles Bibliográficos
Autores principales: Singh, Avinash K., Murmu, Sumit, Krężel, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773336/
https://www.ncbi.nlm.nih.gov/pubmed/36570257
http://dx.doi.org/10.1021/acsomega.2c05652