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ADAR1p110 promotes Enterovirus D68 replication through its deaminase domain and inhibition of PKR pathway

BACKGROUND: Severe respiratory and neurological diseases caused by human enterovirus D68 (EV-D68) pose a serious threat to public health, and there are currently no effective drugs and vaccines. Adenosine deaminase acting on RNA1 (ADAR1) has diverse biological functions in various viral infections,...

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Detalles Bibliográficos
Autores principales: Zhang, Kehan, Wang, Siyuan, Chen, Tingting, Tu, Zeng, Huang, Xia, Zang, Guangchao, Wu, Chun, Fan, Xinyue, Liu, Jia, Tian, Yunbo, Cheng, Yong, Lu, Nan, Zhang, Guangyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773460/
https://www.ncbi.nlm.nih.gov/pubmed/36550502
http://dx.doi.org/10.1186/s12985-022-01952-6