Evaluation of two-stage designs of Phase 2 single-arm trials in glioblastoma: a systematic review

BACKGROUND: Due to economical and ethical reasons, the two-stage designs have been widely used for Phase 2 single-arm trials in oncology because the designs allow us to stop the trial early if the proposed treatment is likely to be ineffective. Nonetheless, none has examined the usage for published...

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Detalles Bibliográficos
Autores principales: Yoo, Wonsuk, Kim, Seongho, Garcia, Michael, Mehta, Shwetal, Sanai, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773486/
https://www.ncbi.nlm.nih.gov/pubmed/36550391
http://dx.doi.org/10.1186/s12874-022-01810-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773486/
https://www.ncbi.nlm.nih.gov/pubmed/36550391
http://dx.doi.org/10.1186/s12874-022-01810-7

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