Central monitoring of depression and anxiety symptoms reduces placebo responses in depression clinical trials: A post hoc exploratory analysis of data from the phase III CCT‐004 trial of vortioxetine

AIM: Clinical trials of antidepressants often fail to demonstrate their efficacy versus placebo, suggesting that patient selection based on physician ratings of depression may contribute to a high placebo response. METHODS: In the CCT‐004 trial of vortioxetine, central monitoring was employed to com...

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Detalles Bibliográficos
Autores principales: Watanabe, Yoshinori, Nishimura, Akira, Kikuchi, Toshiaki, Sawada, Norifusa, Imazaki, Manami, Inada, Isao, Watanabe, Koichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773757/
https://www.ncbi.nlm.nih.gov/pubmed/36151855
http://dx.doi.org/10.1002/npr2.12288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773757/
https://www.ncbi.nlm.nih.gov/pubmed/36151855
http://dx.doi.org/10.1002/npr2.12288

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