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Synthesis, Characterization, DFT Mechanistic Study, Antimicrobial Activity, Molecular Modeling, and ADMET Properties of Novel Pyrazole-isoxazoline Hybrids

[Image: see text] A series of new heterocycle hybrids incorporating pyrazole and isoxazoline rings was successfully synthesized, characterized, and evaluated for their antimicrobial responses. The synthesized compounds were obtained utilizing N-alkylation and 1,3-dipolar cycloaddition reactions, as...

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Detalles Bibliográficos
Autores principales: Chalkha, Mohammed, Nour, Hassan, Chebbac, Khalid, Nakkabi, Asmae, Bahsis, Lahoucine, Bakhouch, Mohamed, Akhazzane, Mohamed, Bourass, Mohamed, Chtita, Samir, Bin Jardan, Yousef A., Augustyniak, Maria, Bourhia, Mohammed, Aboul-Soud, Mourad A.M., El Yazidi, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773794/
https://www.ncbi.nlm.nih.gov/pubmed/36570248
http://dx.doi.org/10.1021/acsomega.2c05788