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Reduced blood-brain barrier penetration of acne vulgaris antibiotic sarecycline compared to minocycline corresponds with lower lipophilicity

BACKGROUND: Vestibular side effects such as dizziness and vertigo can be a limitation for some antibiotics commonly used to treat acne, rosacea, and other dermatology indications. OBJECTIVE: Unlike minocycline, which is a second-generation tetracycline, sarecycline, a narrow-spectrum third-generatio...

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Detalles Bibliográficos
Autores principales: Grada, Ayman, Del Rosso, James Q., Moore, Angela Y., Stein Gold, Linda, Harper, Julie, Damiani, Giovanni, Shaw, Katharina, Obagi, Sabine, Salem, Raidah J., Tanaka, S. Ken, Bunick, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773825/
https://www.ncbi.nlm.nih.gov/pubmed/36569144
http://dx.doi.org/10.3389/fmed.2022.1033980