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Successful treatment of rituximab-unresponsive elderly-onset neuromyelitis optica spectrum disorder and hypogammaglobulinemia with ofatumumab plus intravenous immunoglobulin therapy in a patient with mutant FCGR3A genotype: A case report

BACKGROUND: Elderly-onset neuromyelitis optica spectrum disorder (NMOSD) is a rare entity that poses a therapeutic challenge. We report a case of elderly-onset NMOSD with mutant FCGR3A genotype who was successfully treated with ofatumumab after multiple episodes of relapse. CASE REPORT: The patient...

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Detalles Bibliográficos
Autores principales: Zhang, Weihe, Jiao, Yujuan, Jiao, Jinsong, Jin, Ming, Peng, Dantao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773878/
https://www.ncbi.nlm.nih.gov/pubmed/36569904
http://dx.doi.org/10.3389/fimmu.2022.1047992