Solid-state NMR of paired helical filaments formed by the core tau fragment tau(297-391)

Aggregation of the tau protein into fibrillar cross-β aggregates is a hallmark of Alzheimer’s diseases (AD) and many other neurodegenerative tauopathies. Recently, several core structures of patient-derived tau paired helical filaments (PHFs) have been solved revealing a structural variability that...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Hilaly, Youssra K., Hurt, Connor, Rickard, Janet E., Harrington, Charles R., Storey, John M. D., Wischik, Claude M., Serpell, Louise C., Siemer, Ansgar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774000/
https://www.ncbi.nlm.nih.gov/pubmed/36570831
http://dx.doi.org/10.3389/fnins.2022.988074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774000/
https://www.ncbi.nlm.nih.gov/pubmed/36570831
http://dx.doi.org/10.3389/fnins.2022.988074

Ejemplares similares