Cargando…

The molecular basis of the dichotomous functionality of MAP4K4 in proliferation and cell motility control in cancer

The finely tuned integration of intra- and extracellular cues by components of the mitogen-activated protein kinase (MAPK) signaling pathways controls the mutually exclusive phenotypic manifestations of uncontrolled growth and tumor cell dissemination. The Ser/Thr kinase MAP4K4 is an upstream integr...

Descripción completa

Detalles Bibliográficos
Autores principales: Jovanovic, Dejana, Yan, Shen, Baumgartner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774001/
https://www.ncbi.nlm.nih.gov/pubmed/36568222
http://dx.doi.org/10.3389/fonc.2022.1059513