Loss of ARHGAP15 affects the directional control of migrating interneurons in the embryonic cortex and increases susceptibility to epilepsy

GTPases of the Rho family are components of signaling pathways linking extracellular signals to the control of cytoskeleton dynamics. Among these, RAC1 plays key roles during brain development, ranging from neuronal migration to neuritogenesis, synaptogenesis, and plasticity. RAC1 activity is positi...

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Detalles Bibliográficos
Autores principales: Liaci, Carla, Camera, Mattia, Zamboni, Valentina, Sarò, Gabriella, Ammoni, Alessandra, Parmigiani, Elena, Ponzoni, Luisa, Hidisoglu, Enis, Chiantia, Giuseppe, Marcantoni, Andrea, Giustetto, Maurizio, Tomagra, Giulia, Carabelli, Valentina, Torelli, Federico, Sala, Mariaelvina, Yanagawa, Yuchio, Obata, Kunihiko, Hirsch, Emilio, Merlo, Giorgio R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774038/
https://www.ncbi.nlm.nih.gov/pubmed/36568982
http://dx.doi.org/10.3389/fcell.2022.875468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774038/
https://www.ncbi.nlm.nih.gov/pubmed/36568982
http://dx.doi.org/10.3389/fcell.2022.875468

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