A Defucosylated Anti-EpCAM Monoclonal Antibody (EpMab-37-mG(2a)-f) Exerts Antitumor Activity in Xenograft Model

The epithelial cell adhesion molecule (EpCAM) is a stem cell and carcinoma antigen, which mediates cellular adhesion and proliferative signaling by the proteolytic cleavage. In contrast to low expression in normal epithelium, EpCAM is frequently overexpressed in various carcinomas, which correlates...

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Detalles Bibliográficos
Autores principales: Asano, Teizo, Tanaka, Tomohiro, Suzuki, Hiroyuki, Li, Guanjie, Ohishi, Tomokazu, Kawada, Manabu, Yoshikawa, Takeo, Kaneko, Mika K., Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774109/
https://www.ncbi.nlm.nih.gov/pubmed/36546899
http://dx.doi.org/10.3390/antib11040074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774109/
https://www.ncbi.nlm.nih.gov/pubmed/36546899
http://dx.doi.org/10.3390/antib11040074

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