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Screening of Novel Antimicrobial Diastereomers of Azithromycin–Thiosemicarbazone Conjugates: A Combined LC-SPE/Cryo NMR, MS/MS and Molecular Modeling Approach

A well-known class of antibacterials, 14- and 15-membered macrolides are widely prescribed to treat upper and lower respiratory tract infections. Azithromycin is a 15-membered macrolide antibiotic possessing a broad spectrum of antibacterial potency and favorable pharmacokinetics. Bacterial resistan...

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Detalles Bibliográficos
Autores principales: Habinovec, Iva, Mikulandra, Ivana, Pranjić, Paula, Kazazić, Saša, Paljetak, Hana Čipčić, Barišić, Antun, Bertoša, Branimir, Bukvić, Mirjana, Novak, Predrag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774193/
https://www.ncbi.nlm.nih.gov/pubmed/36551395
http://dx.doi.org/10.3390/antibiotics11121738