The Effect of the Ala16Val Mutation on the Secondary Structure of the Manganese Superoxide Dismutase Mitochondrial Targeting Sequence

Manganese Superoxide Dismutase (MnSOD) represents a mitochondrial protein that scavenges reactive oxygen species (ROS) responsible for oxidative stress. A known single nucleotide polymorphism (SNP) rs4880 on the SOD2 gene, causing a mutation from alanine to valine (Ala16Val) in the primary structure...

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Detalles Bibliográficos
Autores principales: Broz, Matic, Furlan, Veronika, Lešnik, Samo, Jukič, Marko, Bren, Urban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774195/
https://www.ncbi.nlm.nih.gov/pubmed/36552556
http://dx.doi.org/10.3390/antiox11122348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774195/
https://www.ncbi.nlm.nih.gov/pubmed/36552556
http://dx.doi.org/10.3390/antiox11122348

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