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The Effect of the Ala16Val Mutation on the Secondary Structure of the Manganese Superoxide Dismutase Mitochondrial Targeting Sequence

Manganese Superoxide Dismutase (MnSOD) represents a mitochondrial protein that scavenges reactive oxygen species (ROS) responsible for oxidative stress. A known single nucleotide polymorphism (SNP) rs4880 on the SOD2 gene, causing a mutation from alanine to valine (Ala16Val) in the primary structure...

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Detalles Bibliográficos
Autores principales:	Broz, Matic, Furlan, Veronika, Lešnik, Samo, Jukič, Marko, Bren, Urban
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774195/ https://www.ncbi.nlm.nih.gov/pubmed/36552556 http://dx.doi.org/10.3390/antiox11122348

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