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A Perspective on Newly Emerging Proteolysis-Targeting Strategies in Antimicrobial Drug Discovery

Targeted protein degradation is a new aspect in the field of drug discovery. Traditionally, developing an antibiotic includes tedious and expensive processes, such as drug screening, lead optimization, and formulation. Proteolysis-targeting chimeras (PROTACs) are new-generation drugs that use the pr...

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Detalles Bibliográficos
Autores principales: Venkatesan, Janarthanan, Murugan, Dhanashree, Rangasamy, Loganathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774230/
https://www.ncbi.nlm.nih.gov/pubmed/36551374
http://dx.doi.org/10.3390/antibiotics11121717