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A Perspective on Newly Emerging Proteolysis-Targeting Strategies in Antimicrobial Drug Discovery
Targeted protein degradation is a new aspect in the field of drug discovery. Traditionally, developing an antibiotic includes tedious and expensive processes, such as drug screening, lead optimization, and formulation. Proteolysis-targeting chimeras (PROTACs) are new-generation drugs that use the pr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774230/ https://www.ncbi.nlm.nih.gov/pubmed/36551374 http://dx.doi.org/10.3390/antibiotics11121717 |