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Neuronal Oxidative Stress Promotes α-Synuclein Aggregation In Vivo

Both genetic and environmental factors increase risk for Parkinson’s disease. Many of the known genetic factors influence α-synuclein aggregation or degradation, whereas most of the identified environmental factors produce oxidative stress. Studies using in vitro approaches have identified mechanism...

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Detalles Bibliográficos
Autores principales: Won, Seok Joon, Fong, Rebecca, Butler, Nicholas, Sanchez, Jennifer, Zhang, Yiguan, Wong, Candance, Tambou Nzoutchoum, Olive, Huynh, Annie, Pan, June, Swanson, Raymond A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774295/
https://www.ncbi.nlm.nih.gov/pubmed/36552674
http://dx.doi.org/10.3390/antiox11122466