SLC7A11 as a Gateway of Metabolic Perturbation and Ferroptosis Vulnerability in Cancer

SLC7A11 is a cell transmembrane protein composing the light chain of system xc(−), transporting extracellular cystine into cells for cysteine production and GSH biosynthesis. SLC7A11 is a critical gateway for redox homeostasis by maintaining the cellular levels of GSH that counter cellular oxidative...

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Detalles Bibliográficos
Autores principales: Lee, Jaewang, Roh, Jong-Lyel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774303/
https://www.ncbi.nlm.nih.gov/pubmed/36552652
http://dx.doi.org/10.3390/antiox11122444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774303/
https://www.ncbi.nlm.nih.gov/pubmed/36552652
http://dx.doi.org/10.3390/antiox11122444

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