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SLC7A11 as a Gateway of Metabolic Perturbation and Ferroptosis Vulnerability in Cancer
SLC7A11 is a cell transmembrane protein composing the light chain of system xc(−), transporting extracellular cystine into cells for cysteine production and GSH biosynthesis. SLC7A11 is a critical gateway for redox homeostasis by maintaining the cellular levels of GSH that counter cellular oxidative...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774303/ https://www.ncbi.nlm.nih.gov/pubmed/36552652 http://dx.doi.org/10.3390/antiox11122444 |