MLN-4760 Induces Oxidative Stress without Blood Pressure and Behavioural Alterations in SHRs: Roles of Nfe2l2 Gene, Nitric Oxide and Hydrogen Sulfide

Reduced angiotensin 1–7 bioavailability due to inhibition of angiotensin-converting enzyme 2 (ACE2) may contribute to increased mortality in hypertensive individuals during COVID-19. However, effects of ACE2 inhibitor MLN-4760 in brain functions remain unknown. We investigated the selected behaviour...

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Detalles Bibliográficos
Autores principales: Kluknavsky, Michal, Micurova, Andrea, Cebova, Martina, Şaman, Ezgi, Cacanyiova, Sona, Bernatova, Iveta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774314/
https://www.ncbi.nlm.nih.gov/pubmed/36552591
http://dx.doi.org/10.3390/antiox11122385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774314/
https://www.ncbi.nlm.nih.gov/pubmed/36552591
http://dx.doi.org/10.3390/antiox11122385

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